Geven, Christopher: search on Z-Library

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1

Safety, tolerability and pharmacokinetics/-dynamics of the adrenomedullin antibody Adrecizumab in a first-in-human study and during experimental human endotoxemia in healthy subjects

Geven, Christopher, van Lier, Dirk, Blet, Alice, Peelen, Roel, ten Elzen, Bas, Mebazaa, Alexandre, Kox, Matthijs, Pickkers, Peter

Journal:

British Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 574 KB

english, 2018

2

Experimental human endotoxemia as a model of systemic inflammation

van Lier, Dirk, Geven, Christopher, Leijte, Guus P., Pickkers, Peter

Journal:

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

3

A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2)

Geven, Christopher, Blet, Alice, Kox, Matthijs, Hartmann, Oliver, Scigalla, Paul, Zimmermann, Jens, Marx, Gernot, Laterre, Pierre-François, Mebazaa, Alexandre, Pickkers, Peter

Journal:

Year:

2019

Language:

english

File:

PDF, 393 KB

english, 2019

4

The mechanism of action of the adrenomedullin-binding antibody adrecizumab

Geven, Christopher, Pickkers, Peter

Journal:

Critical Care (BioMed Central)

Year:

2018

Language:

english

File:

PDF, 488 KB

english, 2018

5

Imaging, myeloid precursor immortalization, and genome editing for defining mechanisms of leukocyte recruitment in vivo

Gran, Sandra, Honold, Lisa, Fehler, Olesja, Zenker, Stefanie, Eligehausen, Sarah, Kuhlmann, Michael T., Geven, Edwin, den Bosch, Martijn van, van Lent, Peter, Spiekermann, Christoph, Hermann, Sven, Vo

Journal:

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

6

Micro-porous composite scaffolds of photo-crosslinked poly(trimethylene carbonate) and nano-hydroxyapatite prepared by low-temperature extrusion-based additive manufacturing

Geven, Mike A., Sprecher, Christoph, Guillaume, Olivier, Eglin, David, Grijpma, Dirk W.

Journal:

Polymers for Advanced Technologies

Year:

2016

Language:

english

File:

PDF, 299 KB

english, 2016

7

Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study

Mebazaa, Alexandre, Geven, Christopher, Hollinger, Alexa, Wittebole, Xavier, Chousterman, Benjamin Glen, Blet, Alice, Gayat, Etienne, Hartmann, Oliver, Scigalla, Paul, Struck, Joachim, Bergmann, Andre

Journal:

Year:

2018

Language:

english

File:

PDF, 989 KB

english, 2018

8

Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis

Geven, Christopher, Kox, Matthijs, Pickkers, Peter

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 976 KB

english, 2018

9

Orbital floor repair using patient specific osteoinductive implant made by stereolithography

Guillaume, Olivier, Geven, Mike A., Varjas, Viktor, Varga, Peter, Gehweiler, Dominic, Stadelmann, Vincent A., Smidt, Tanja, Zeiter, Stephan, Sprecher, Christoph, Bos, Ruud R.M., Grijpma, Dirk W., Alin

Journal:

Year:

2019

File:

PDF, 15.26 MB

2019

10

A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2)

Geven, Christopher, Blet, Alice, Kox, Matthijs, Hartmann, Oliver, Scigalla, Paul, Zimmermann, Jens, Marx, Gernot, Laterre, Pierre-François, Mebazaa, Alexandre, Pickkers, Peter

Journal:

Year:

2019

File:

PDF, 393 KB

2019

11

Adrenomedullin in heart failure: pathophysiology and therapeutic application

Voors, Adriaan A., Kremer, Daan, Geven, Christopher, ter Maaten, Jozine M., Struck, Joachim, Bergmann, Andreas, Pickkers, Peter, Metra, Marco, Mebazaa, Alexandre, Düngen, Hans-Dirk, Butler, Javed

Journal:

European Journal of Heart Failure

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

12

Adrecizumab, a non-neutralizing anti-adrenomedullin antibody, improves haemodynamics and attenuates myocardial oxidative stress in septic rats

Blet, Alice, Deniau, Benjamin, Geven, Christopher, Sadoune, Malha, Caillard, Anaïs, Kounde, Paul-Robert, Polidano, Evelyne, Pickkers, Peter, Samuel, Jane-Lise, Mebazaa, Alexandre

Journal:

Intensive Care Medicine Experimental

Year:

2019

Language:

english

File:

PDF, 2.80 MB

english, 2019

13

Effects of the Humanized Anti-Adrenomedullin Antibody Adrecizumab (HAM8101) on Vascular Barrier Function and Survival in Rodent Models of Systemic Inflammation and Sepsis

Geven, Christopher, Peters, Esther, Schroedter, Mathias, Struck, Joachim, Bergmann, Andreas, McCook, Oscar, Radermacher, Peter, Kox, Matthijs, Pickkers, Peter

Journal:

Year:

2018

Language:

english

File:

PDF, 3.51 MB

english, 2018

14

Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis

Geven, Christopher, Bergmann, Andreas, Kox, Matthijs, Pickkers, Peter

Journal:

Year:

2018

Language:

english

File:

PDF, 624 KB

english, 2018

15

Association between probiotics and enteral nutrition in an experimental acute pancreatitis model in rats

van Baal, Mark C., van Rens, Michiel J., Geven, Christopher B., van de Pol, Francien M., van den Brink, Ilona W., Hannink, Gerjon, Nagtegaal, Iris D., Peters, Wilbert H., Rijkers, Ger T., Gooszen, Hei

Journal:

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

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